Study of deamidation of cartilage extracellular matrix proteins to investigate cartilage turnover
نویسندگان
چکیده
منابع مشابه
Cartilage: Biomimetic Study of the Extracellular Matrix
Cartilage is a complex biological tissue that exhibits gel-like behavior. Its primary biological function is providing compressive resistance to external loading and nearly frictionless lubrication of joints. In this study, we model cartilage extracellular matrix using a biomimetic system. We demonstrate that poly(vinyl) alcohol (PVA) hydrogels are robust biomaterials exhibiting mechanical and ...
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Articular cartilage is a low-friction, load-bearing tissue located at joint surfaces. The extracellular matrix (ECM) of cartilage consists of a fibrous collagen network, which is pre-stressed by the osmotic swelling pressure exerted by negatively charged proteoglycan aggregates embedded in the collagen network. The major proteoglycan is the bottlebrush shaped aggrecan, which forms complexes wit...
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ژورنال
عنوان ژورنال: Osteoarthritis and Cartilage
سال: 2013
ISSN: 1063-4584
DOI: 10.1016/j.joca.2013.02.237